Vous trouverez dans ce chapitre une liste des publications parues au cours des cinq dernières années et auxquelles les membres de notre équipe ont grandement contribué. Seuls les articles publiés dans des revues scientifiques sont indiqués ci-dessous :

Benedict C, Shostak A, Lange T, Brooks SJ, Schiöth HB, Schultes B, Born J, Oster H, Hallschmid M (2012). Diurnal Rhythm of Circulating Nicotinamide Phosphoribosyltransferase (Nampt/Visfatin/PBEF): Impact of Sleep Loss and Relation to Glucose Metabolism. J Clin Endocrinol Metab (in press). 

Ott V, Friedrich M, Zemlin J, Lehnert H, Schultes B, Born J, Hallschmid M (2011). Meal anticipation potentiates postprandial ghrelin suppression in humans. Psychoneuroendocrinology (in press). 

Benedict C, Brede S, Schiöth H, Lehnert H, Schultes B, Born J, Hallschmid J (2011). Intranasales Insulin steigert die nahrungsinduzierte Thermogenese und mindert die postprandiale Insulinantwort beim Menschen. Spitzenforschung in der Diabetologie : 26-32. 

Ott V, Benedict C, Schultes B, Born J, Hallschmid M (2011). Intranasal administration of insulin to the brain impacts cognitive function and peripheral metabolism. Diabetes Obes Metab (in press)

Tarantino I, Warschkow R, Steffen T, Bisang P, Schultes B, Thurnheer M (2011). Is Routine Cholecystectomy Justified in Severely Obese Patients Undergoing a Laparoscopic Roux-en-Y Gastric Bypass Procedure? A Comparative Cohort Study. Obes Surg (in press).

Benedict C, Hallschmid M, Lassen A, Mahnke C, Schultes B, Schiöth HB, Born J, Lange T (2011). Acute sleep deprivation reduces energy expenditure in healthy men. Am J Clin Nutr. 93:1229-36

Benedict C, Frey WH 2nd, Schiöth HB, Schultes B, Born J, Hallschmid M (2011). Intranasal insulin as a therapeutic option in the treatment of cognitive impairments Experimental Gerontology. Exp Gerontol 46(2-3): 112-115.

Benedict C, Brede S, Schiöth HB, Lehnert H, Schultes B, Born J, Hallschmid M (2011). Intranasal insulin enhances postprandial thermogenesis and lowers postprandial serum insulin levels in healthy men. Diabetes 60(1): 114-8

 Schmid SM, Hallschmid M, Jauch-Chara K, Wilms B, Lehnert H, Born J, Schultes B (2011). Disturbed glucoregulatory response to food intake after moderate sleep restriction. Sleep 34: 371-377

Schmid SM, Schultes B (2011). Disturbed sleep as a risk factor for metabolic syndrome. Internist (Berl) 52: 383-388

Benedict C, Jacobsson JA, Rönnemaa E, Sällman-Almén M, Brooks S, Schultes B, Fredriksson R, Lannfelt L, Kilander L, Schiöth HB (2011). The fat mass and obesity gene is linked to reduced verbal fluency in overweight and obese elderly men. Neurobiol Aging 32:1159e1-5

Wilms B, Meffert K S, Schultes B (2010). Procain infusion in pain treatment of acute pancreatitis: a randomized, placebo-controlled double-blind trial. Dtsch Med Wochenschr; 135:2290-5 

Schultes B, Jauch-Chara K (2010). Sleep and the response to hypoglycaemia. Best Pract Res Clin Endocrinol Metab. 24(5):801-15

Schultes B (2010). Hypoglykämien nach bariatrischen Operationen – Verwandt mit dem Dumping-Syndrom? Leading Opinions Diabetes & Stoffwechsel 3: 11 – 14

Benedict C, Brede S, Schiöth HB, Lehnert H, Schultes B, Born J, Hallschmid M (2010). Intranasal insulin enhances postprandial thermogenesis and lowers postprandial serum insulin levels in healthy men. Diabetes (in press)

Ernst B, Thurnheer M, Schultes B (2010). Fertilität und Schwangerschaft nach bariatrischer Chirurgie zur Behandlung der hochgradigen Adipositas. Aktuel Ernahrungsmed 35: 220 - 226

Loebig M, Klement J, Schmoller A, Betz S, Heuck N, Schweiger U, Peters A, Schultes B, Oltmanns KM (2010). Evidence for a Relationship between VEGF and BMI Independent of Insulin Sensitivity by Glucose Clamp Procedure in a Homogenous Group Healthy Young Men. PLoS 5(9).

Benedict C, Frey WH 2nd, Schiöth HB, Schultes B, Born J, Hallschmid M (2010). Intranasal insulin as a therapeutic option in the treatment of cognitive impairments Experimental Gerontology. Exp Gerontol (in press)

Schmid SM, Hallschmid M, Lehnert H, Schultes B (2010)Response to the Letter to the editor “Short sleep duration is associated with reduced leptin levels and increased adiposity: results from the Quebec family study” by Chaput et al. Am J Clin Nutr 91: 823-824

Schultes B, Ernst B, Wilms B, Thurnheer M, Hallschmid M (2010). Hedonic hunger is increased in severely obese patients and is reduced after gastric bypass surgery. Am J Clin Nutr 92: 227 - 83

Wilms B, Schmid SM, Ernst B, Thurnheer M, Mueller MJ, Schultes B (2010) Poor prediction of resting energy expenditure in obese women by established equations. Metabolism 59: 1181 - 9.

Schultes B, Frick J, Ernst B, Stefan N, Fritsche A (2010). The Effect of 6-Weeks of Aerobic Exercise Training on Serum Fetuin-A levels in Non-Diabetic Obese Women. Exp Clin Endocrinol Diabetes (in press)

Hallschmid M, Jauch-Chara K, Korn O, Mölle M, Rasch B, Born J, Schultes B, Kern W (2010). Euglycemic infusion of insulin detemir compared with human insulin appears to increase direct current brain potential response and reduces food intake while inducing similar systemic effects. Diabetes 59:1101-7

Schultes B, Ernst B, Thurnheer M (2010) Bariatrische Chirurgie und Schwangerschaft. Schweizer Medizinisches Forum 10: 304 - 7

Ernst B, Thurnheer M, Schmid SM, Schultes B (2010) Response to the Letter to the Editor "Bariatric Surgery and the Assessment of Copper and Zinc Nutriture" by Leslie M. Klevay. Obes Surg 20: 674-675

Jauch-Chara K, Hallschmid M, Schmid SM, Bandorf N, Born J, Schultes B (2010)
Sleep loss does not aggravate the deteriorating effect of hypoglycemia on neurocognitive function in healthy men. Psychoneuroendocrinology 35: 624-628

Leschka S, Stinn B, Schmid F, Schultes B, Thurnheer M, Baumueller S, Stolzmann P, Scheffel H, Flohr TG, Wildermuth S, Alkadhi H (2009) Dual source CT coronary angiography in severely obese patients: trading off temporal resolution and image noise. Investigative radiology 44: 720-727

Schmid SM, Jauch-Chara K, Hallschmid M, Schultes B (2009). Mild sleep resection acutely reduces plasma glucagon levels in healthy men. J Clin Endocrinol Metab 94: 5169-5173

Schmid SM, Hallschmid M, Jauch-Chara K, Wilms B, Benedict C, Lehnert H, Born J, Schultes B (2009)
Short-term sleep loss reduces physical activity under free-living conditions, but does not increase food intake under time-deprived laboratory conditions in healthy men. Am J Clin Nutr 90: 1476-1482

Ernst B, Thurnheer M, Schultes B (2009)
Copper deficiency after gastric bypass surgery. Obesity 17: 1980-1981

Hallschmid M, Schultes B (2009)
Central nervous insulin resistance: a promising target in the treatment of metabolic and cognitive disorders? Diabetologia 52: 2264-2269

Ernst B, Thurnheer M, Schmid SM, Schultes B (2009)
Evidence for the necessity to systematically assess micronutrient status prior to bariatric surgery. Obes Surg 19:66-73

Benedict C, Kern W, Schmid SM, Schultes B, Bern J, Hallschmid M (2009)
Early morning rise in hypothalamic-pituitary-adrenal activity: a role for maintaining the brain’s energy balance. Psychoneuroendocrinology 34:455-62

Ernst B, Thurnheer M, Schmid SM, Wilms B, Schultes B (2009)
Seasonal variation in the deficiency of 25-hydroxyvitamin D3 in midly to extremly obese subjects, Obes Surg 19:180-3

Klement J, Pais I, Hallschmid M, Hubold C, Knispel A, Oltmanns KM, Schultes B, Born J, Peters A (2009)
Blocking AMPA receptor signalling by caroverine infusion does not affect counter-regulation of hypoglycaemia in healthy men. Diabetologia 52:1192-6

Ernst B, Thurnheer M, Wilms B, Schultes B (2009)
Differential changes in dietary habits after gastric bypass versus gastric banding operations. Obes Surg 19:274-80

Schmoller A, Eberhardt F, Jauch-Chara K, Schweiger U, Zabel P, Peters A, Schultes B, Oltmanns KM (2009)
Continuous positive airway pressure therapy decreases evening cortisol concentrations in patients with severe obstructive sleep apnea. Metabolism 58:848-53

Ernst B, Thurnheer M, Schultes B (2009)
Basal serum prolactin levels in obesity – unrelated to parameters of the metabolic syndrome and unchanged after massive weight loss. Obes Surg 19:1159-62

Bremer JP, Jauch-Chara K, Hallschmid M, Schmid S, Schultes B (2009)
Hypoglycemia unawareness in older compared with middle-aged patients with type 2 diabetes. Diabetes care 32:1513-7

Hubold C, Lang UE, Gehring H, Schultes B, Schweiger U, Peters A, Hellweg R, Oltmanns KM (2009)
Increased serum brain-derived neurotrophic factor protein upon hypoxia in healthy young men. J Neural Transm 116:1221-5

Schmoller A, Voss M, Gehring H, Rudolf S, Schweiger U, Schultes B, Oltmanns KM (2009)
Short hypoxia does not affect plasma leptin in healthy men under euglycemic clamp conditions. Int J Endocrinol 2009, Article ID 270698, 6 pages

Schultes B, Ernst B, Schmid F, Thurnheer M (2009)
Distal gastric bypass surgery for the treatment of hypothalamic obesity after childhood craniopharyngioma. Eur J Endocrinol 161:201-6

Hallschmid M, Benedict C, Schultes B, Born J, Kern W. (2008)
Obese men respond to cognitive but not to catabolic brain insulin signaling. Int J Obes Relat Metab Disord 32:275-82

Oltmanns KM, Melchert UH, Scholand-Engler HG, Schultes B, Schweiger U, Peters A. (2008)
Divergent effects of hyper- and hypoglycemia on circulating vascular endothelial growth factor in humans. Metabolism 57:90-4.

Oltmanns KM, Melchert UH, Scholand-Engler HG, Howitz MC, Schultes B, Schweiger U, Hohagen F, Born J, Peters A, Pellerin L. (2008)
Differential energetic response of brain vs. skeletal muscle upon glycemic variations in healthy humans. Am J Physiol Regul Integr Comp Physiol 294:R12-6

Schmid SM, Jauch-Chara K, Hallschmid M, Oltmanns KM, Born J, Schultes B. (2008)
Short-term nocturnal hypoglycemia increases morning food intake in healthy humans. Diabetic medicine 25:232-5.

Jauch-Chara K, Schmid SM, Hallschmid M, Born J, Schultes B (2008)
Altered neuroendocrine sleep architecture in patients with type 1 diabetes. Diabetes Care 31:1183-8.

Benedict C, Kern W, Schultes B, Born J, Hallschmid M (2008)
Differential sensitivity of men and women to anorexigenic and memory improving effects of intranasal insulin. J Clin Endocrinol Metab 93:1339-44.

Schmid SM, Jauch-Chara K, Hallschmid M, Born J, Schultes B (2008)
A single night of sleep deprivation increases ghrelin levels and feelings of hunger in normal-weight healthy men. J Sleep Res 17:331-4

Pais I, Hubold C, Hallschmid M, Letterer C, Oltmanns KM, Schultes B, Born J, Peters A (2008)
Blocking NMDA receptor signaling does not decrease hormonal counterregulation to hypoglycemia in humans. Psychoneuroendocrinology 33:1069-76

Schmid SM, Jauch-Chara K, Hallschmid M, Born J, Schultes B (2008)
Lactate overrides central nervous but not ß-cell glucose sensing in humans, Metabolism 57:1733-9

Hallschmid M, Benedict C, Schultes B, Perras B, Fehm HL, Kern W, Born J. (2008)
Towards the therapeutic use of intranasal neuropeptide administration in metabolic and cognitive disorders. Regul Pept 149: 79-83

Benedict C, Hallschmid M, Schmitz K, Schultes B, Ratter F, Fehm HL, Born J, Kern W. (2007)
Intranasal Insulin improves memory in humans: Superiority of insulin aspart. Neuropsychopharmacology 32:239-43

Benedict C, Ghio AJ, Gehring H, Schultes B, Peters A, Oltmanns KM (2007)
Transient hypoxia downregulates circulating prohepcidin concentrations in healthy young men. Haematology 92:125-127

Pais I, Hallschmid M, Chara K, Schmid SM, Oltmanns KM, Peters A, Born J, Schultes B. (2007)
Mood and cognitive functions during acute euglycaemia and mild hyperglycaemia in type 2 diabetic patients. Exp Clin Endocrinol Diabetes 115:42-6

Schultes B, Jauch-Chara K, Gais S, Hallschmid M, Reiprich E, Kern W, Oltmanns KM, Peters A, Fehm HL, Born J. (2007)
Defective awakening response to nocturnal hypoglycemia in patients with type 1 diabetes mellitus. PLoS Med 4:e69

Jauch-Chara K, Hallschmid M, Schmid SM, Oltmanns KM, Peters A, Born J, Schultes B. (2007)
Plasma glucagon decreases during night-time sleep in Type 1 diabetic patients and healthy control subjects. Diabet Med. 24:684-7

Jauch-Chara K, Hallschmid M, Gais S, Oltmanns KM, Peters A, Born J, Schultes B. (2007)
Awakening and counterregulatory response to hypoglycemia during early and late sleep. Diabetes; 56:1938-42

Jauch-Chara K, Hallschmid M, Gais S, Schmid SM, Oltmanns KM, Colmorgen C, Born J, Schultes B. (2007)
Hypoglycemia during sleep impairs consolidation of declarative memory in type 1 diabetic and healthy humans. Diabetes Care 30:2040-5

Schmid SM, Hallschmid M, Jauch-Chara K, Bandorf N, Born J, Schultes B. (2007)
Sleep loss alters basal metabolic hormone secretion and modulates the dynamic counterregulatory response to hypoglycemia. J Clin Endocrinol Metab 92:3044-51

Benedict C, Hallschmid M, Schultes B, Born J, Kern W (2007)
Minireview: Intranasal insulin to improve memory function in humans. Neuroendocrinolgy 86:136-42

Schmid S, Hallschmid M, Schultes B (2007)
Sleep loss, obesity and diabetes: a fetal connection? Expert Rev Endocrinol Metab 2:713-715

Therapielexikon Endokrinologie und Stoffwechselkrankheiten, Herausgeber G.K. Stalla, Springer Medizin Verlag Heidelberg, 2007

Schultes B (2007)
Endokrinium. Buchkapitel in Enzyklopädie der Schlafmedizin, Herausgeber H Peter, T Penzel, JH Peter, Springer Medizin Verlag Heidelberg, 2007, S. 349-354

Schultes B (2007)
Körpergewicht. Buchkapitel in Enzyklopädie der Schlafmedizin, Herausgeber H Peter, T Penzel, JH Peter, Springer Medizin Verlag Heidelberg, 2007, S. 646-650

Schultes B (2007)
Comment on: Nathan DM, Buse JB, Davidson MB et al (2006) Management of hyperglycaemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: A consensus statement from the American Diabetes Association and the European Association for the Study of Diabetes. Diabetologia 49: 1711-1721. Diabetologia. 50:225-6.

Bremer JP, Baron M, Peters A, Oltmanns KM, Kern W, Fehm HL, Born J, Schultes B (2006)
Evaluation of sexual dimorphism in hormonal, subjective, and neurocognitive responses to brief hypoglycemia in patients with type 2 diabetes, Metabolism 55:331-8.

Oltmanns KM, Dodt B, Schultes B, Raspe HH, Schweiger U, Born J, Fehm HL, Peters A (2006)
Cortisol correlates with metabolic disturbances in a population study of type 2 diabetic patients, Eur J Endocrinol 154:325-31.

Oltmanns KM, Gehringm H, Rudolf S, Schultes B, Hackenberg C, Schweiger U, Born J, Fehm HL, Peters A (2006)
Acute hypoxia decreases plasma VEGF concentration in healthy humans, Am J Physiol 290:E434-9.

Oltmanns KM, Gehringm H, Rudolf S, Schultes B, Schweiger U, Born J, Fehm HL, Peters A (2006)
Persistent suppression of resting energy expenditure after acute hypoxia, Metabolism 55:669-75.

Hubold C, Oltmanns KM, Schultes B, Jelkmann W, Born J, Fehm HL, Schweiger U, Peters A (2006)
High plasma VEGF relates to low carbohydrate intake in patients with type 2 diabetes. Int J Obes Relat Metab Disord 30:1356-61

Kern W, Benedict C, Schultes B, Plohr F, Moser A, Born J, Fehm HL, Hallschmid M. (2006)
Low cerebrospinal fluid insulin levels in obese humans. Diabetologia 49:2790-2.

Schmid S. und Schultes B (2006)
Schlafmangel – Risikofaktor für Adipositas und Diabetes? Diabetogie 1:122-127

Schultes B, Kern W, Oltmanns KM, Peters A, Gais S, Fehm HL, Born J (2005)
Differential adaptation of human neurocognitive brain functions to recurrent hypoglycemia in healthy men. Psychoneuroendocrinology 30:149-161

Kern W, Peters A, Born J, Fehm HL, Schultes B (2005)
Changes in blood pressure and plasma catecholamine levels during prolonged hyperinsulinaemia. Metabolism 54:391-396

Oltmanns KM, Peters A, Kern W, Fehm HL, Born J, Schultes B (2005)
Preserved inhibitory effect of recurrent hypoglycemia on male gonadotropic axis. Clin Endocrinol 62:217-222

Benedict C, Hallschmid M, Scheibner J, Niemeyer D, Schultes B, Merl V, Fehm HL, Born J, Kern W (2005)
Gut protein uptake and mechanisms of meal induced cortisol release. J Clin Endocrinol Metab 90:1692-1696

Schultes B, Peters A, Kern W, Gais S, Oltmanns KM, Fehm HL, Born J (2005)
Processing of food stimuli is selectively enhanced during insulin-induced hypoglycemia in healthy men. Psychoneuroendocrinology 30:496-504

Merl V, Peters A, Oltmanns KM, Kern W, Born J, Fehm HL, Schultes B (2005)
Serum adiponectin concentrations during a 72-hour fast in over-weight and normal-weight humans. Int J Obes Relat Metab Disord 29:998-1001.

Merl V, Peters A, Oltmanns KM, Kern W, Hubold C, Fehm HL, Born J, Schultes B (2005)
Antecedent hypoglycaemia attenuates vascular endothelial growth factor response to subsequent hypoglycaemia in healthy men. Diabetic medicine 22:1278-81.

Schultes B, Peters A, Hallschmid M, Benedict C, Merl V, Oltmanns KM, Born J, Fehm HL, Kern W (2005)
Modulation of food intake by glucose in patients with type 2 diabetes, Diabetes Care 28:2884-2889

Schultes B, (2005)
Das Problem der Adipositas - so einfach und doch so komplex. Fokus MUL 22:15-22

Schultes B. (2005)
Herauforderung Adipostas. Schleswig-Holsteinisches Ärzteblatt 8:64-68

Schultes B. (2005)
Heil(?)fasten – gesundheitlicher Nutzen ungewiss. Deutsche Apotheker Zeitung 145:74-75

Schultes B, Schmid S, Peters A, Born J, Fehm HL (2005)
Sleep loss and the development of diabetes: A review of current evidence, Exp Clin Endocrinol Diabetes 113:563-7

Merl V, Kern W, Peters A, Oltmanns K, Gais S, Born J, Fehm HL, Schultes B (2004)
Differences between night-time and daytime hypoglycaemia counterregulation in healthy humans. Metabolism, 53:894-8

Oltmanns K, Gehring H., Rudolf S, Schultes B, Rook St., Schweiger U, Born J, Fehm H.L., Peters A. (2004)
Hypoxia causes glucose intolerance in humans Am J Respir Crit Care Med. 169:1231-7

Benedict C, Hallschmid M, Hatke A, Schultes B, Fehm HL, Born J, Kern W (2004)
Intranasal insulin improves memory in humans. Psychoneuroendocrinology, 29:1326-34.

Hallschmid M, Schultes B, Marshall L, Mölle M, Kern W, Bredthauer J, Fehm HL, Born J (2004)
Transcortical direct current potential shift reflects immediate signalling of systemic insulin to the human brain. Diabetes, 53:2202-8.

Perras B, Schultes B, Behn B, Dodt C, Born J, Fehm HL (2004)
Intranasal atrial natriuretic peptide (ANP) acts as central nervous inhibitor of the hypothalamo-pituitary-adrenal (HPA) stress system in humans. J Clin Endocrinol Metab 89: 4642-4648

Merl V, Peters A, Oltmanns KM, Kern W, Hubold C, Hallschmid M, Born J, Fehm HL, Schultes B (2004)
Preserved circadian rhythm of serum insulin concentration at low plasma glucose during fasting in lean and overweight humans. Metabolism 53:1449-1453

Hallschmid M, Benedict B, Schultes B, Fehm HL, Born J, Kern W (2004)
Intranasal insulin reduces body fat in men but not in women. Diabetes 53:3024-3029

Schultes B, Kern W (2004)
Den Mechanismen der zentralvenösen Adaptation an Hypoglykämien auf der Spur. Diabetes-Congress-Report 1:29-33

Peters A, Schweiger U, Pellerin L, Hubold C, Oltmanns K, Conrad M, Schultes B, Born J, Fehm HL (2004)
Selfish brain: Competition for energy resources. Neurosci Biobehav Rev, 28: 143-180

Schultes B, Fehm HL, (2004)
Zirkadiane Rhythmen in der Endokrinologie. Der Internist, 45:983-93

Schultes B, (2004)
Fördert Schlafmangel das Metabolische Syndrome? Diabetes-Congress-Report 6:9-14